<i>Indigofera tinctoria</i> Linn (Fabaceae) attenuates cognitive and behavioral deficits in scopolamine-induced amnesic mice
نویسندگان
چکیده
منابع مشابه
Cognitive-enhancing Properties of Morinda Lucida (rubiaceae) and Peltophorum Pterocarpum (fabaceae) in Scopolamine-induced Amnesic Mice
BACKGROUND Cognitive disorders associated with aging have been successfully managed by African traditional medical practitioners using various plants. This study evaluated the cognitive enhancing potentials of Morinda lucida (L) Rubiaceae and Peltophorum pterocarpum (DC) ex. K Heyne in scopolamine induced amnesic animals. MATERIALS AND METHODS The anti-amnesic activity of the ethyl acetate ex...
متن کاملMefenamic Acid Attenuates Intracerebroventricular Streptozotocin-Induced Cognitive Deficits in the Rat: A Behavioral Analysis
Intracerebroventricular (ICV) injection of streptozotocin (STZ) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic Alzheimer’s disease (SAD). Epidemiological studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) could delay or slow the clinical expression of SAD. Therefore, the benefi...
متن کاملAnethum Graveolens Linn (Umbelliferae) Extract Attenuates Stress-induced Urinary Biochemical Changes and Improves Cognition in Scopolamine- induced Amnesic Rats
Purpose: Anethum graveolens Linn. (Umbelliferae, A. graveolens) is a widely used spice with a long history of traditional medicinal use for the treatment of various ailments. The present study examines the anti-stress and cognition-improving effects of A. graveolens extract in a rat model. Methods: Urinary vanillylmandelic acid (VMA) and ascorbic acid were estimated as biomarkers for evaluating...
متن کاملCognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice.
We examined anti-amnesic activity of the methanolic extract of Cornus officinalis fruits (COT) and a major constituent, loganin using scopolamine-induced (1 mg/kg body weight, s.c.) amnesic mice with both passive avoidance and the Morris water maze tests. Oral treatment of mice with COT (100 mg/kg body weight) and loganin (1 and 2 mg/kg body weight) significantly mitigated scopolamine-induced m...
متن کاملmefenamic acid attenuates intracerebroventricular streptozotocin-induced cognitive deficits in the rat: a behavioral analysis
intracerebroventricular (icv) injection of streptozotocin (stz) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic alzheimer’s disease (sad). epidemiological studies suggest that non-steroidal anti-inflammatory drugs (nsaids) could delay or slow the clinical expression of sad. therefore, the beneficial e...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2016
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v15i4.15